• (3) AFM / LIFE SCIENCE / FAST SCAN
    Dimension Fastscan Bio

    The Dimension FastScan Bio™ Atomic Force Microscope (AFM) breaks longstanding barriers to provide routine high-resolution research of biological dynamics, with temporal resolution up to 3 frames per second for live sample observations. Furthermore, it does this while making the AFM easier to use than ever before.

    These breakthroughs allow many more researchers to observe and study the mechanisms biomolecular machines utilize to perform their biological functions. FastScan Bio’s high-resolution and high-speed scanning provide the best available bio tool for the observation of molecules, proteins, DNA, RNA, living cell membranes and tissues, and many other dynamics studies.

    Greatest Productivity Seen on Any AFM
    „„• FastScan Bio enables high-speed scanning, in conjunction with a seamless user interface for panning, zooming and continuous tracking of samples in fluid to render faster results.
    „„• A single-scan speed slider facilitates immediate access to scan rate control without the complexity of multiparametric adjustment.
    „„• On-board data and image manipulation tools present final data as high-resolution AFM images or experiment session movies.

    Immediate Path to Data Collection on Live Samples
    • „„Smart Engage algorithms take ambiguity out of the experiment process and provide flexibility for commercially available or custom-made probes.
    „„• User interface controls automate laser and detector alignment with a comprehensive workflow for faster time to data.
    • „„Quick sample engaging and immediate imaging are routine.

    More Options to Optimize Biological AFM Experiments
    „„• Innovative FastScan AFM technology enables high-speed scanning and a seamless user interface to render immediate panning, zooming and continuous tracking of samples in fluid.
    „„• FastScan Bio AFM allows direct visualization of biomolecules with an unprecedented combination of spatial and time resolution.

    For more information, please visit:
    https://www.bruker.com/products/surface-and-dimensional-analysis/atomic-force-microscopes/dimension-fastscan-bio/overview.html

  • (4) AFM / LIFE SCIENCE / FLUORESCENCE
    BioScope Resolve

    The BioAFM with Highest Resolution and Most Complete Biomechanics
    The BioScope Resolve™ BioAFM provides the highest resolution imaging, most complete biomechanics capabilities, and fastest scanning of any bioAFM available. Specifically designed for integration onto inverted optical light and confocal microscopes, it enables investigation of a wide range of biological samples, from cells and tissues to molecular and protein structures. The New MIROView™ interface provides unique data sets by combining AFM biomechanics data with real-time confocal and fluorescence microscopy.

    Unrivalled AFM and Optical Synchronization Capabilities
    BioScope Resolve's seamless integration of atomic force microscopy and light microscopy reveals more detail and information of biological samples including mechanical properties. The system's unique design makes combined optical and AFM research easy with its open access to the sample, single instrument setup, and correlated data collection and analysis. Researchers can now perfectly connect real-time optical images with AFM imaging.

    The new MIROView graphical interface and ScanAsyst-Cell mode ensure expert data generation, regardless of the user’s AFM experience level. Other features include:
    • Integrates with all major microscope models and optical techniques
    • Single, integrated view and operation controls for AFM or optical microscope
    • Syncronized AFM images, force maps and single force curves with optical images and data
    • Point-and-click setup for automated force and imaging measurements
    • Video creation of experiments showing optical and AFM results
    • BioAFM accessories and PeakForce Tapping probes to meet every application
    • PeakForce Modes

    For more information, please visit:
    https://www.bruker.com/products/surface-and-dimensional-analysis/atomic-force-microscopes/bioscope-resolve/overview.html

  • AFM / FAST SCAN
    Dimension Fastscan

    The Dimension FastScan® delivers, for the first time, extreme imaging speed without loss of resolution, loss of force control, added complexity, or additional operating costs. This tip-scanning system provides measurements on both large and small size samples in air or fluids. With the FastScan you can achieve immediate atomic force microscopy images with the expected high resolution of a high-performance AFM, all in a single system. Whether surveying a sample scanning at >125Hz to find the region of interest, or scanning for detail at 1-second per image frame in air or fluids, the Dimension FastScan will redefine your AFM experience.

    Enhanced Nanoscale Automation
    Bruker’s new AutoMET™ software uniquely enables the combination of high-resolution AFM imaging with fast, automated metrology. It provides exceptional ease of use and adaptability for critical-to-quality measurements in high-volume measurement applications. AutoMET includes an intuitive and simple recipe-writing environment that makes it extremely easy to reduce complex measurement routines to simple, push-button operations.

    Delivering High Performance on Any AFM Sample
    • Closed-loop Icon and FastScan scanners keep vertical noise below 30pm and 40pm, respectively, as well as high accuracy with ultra-low drift
    • Sample from subnanometer to hundreds of nanometers in height without loss of resolution

    Whether using the Icon scanner with ultra-low noise and high accuracy, or employing the FastScan scanner for high scan rates, the Dimension FastScan system will expand your laboratory’s capabilities beyond that of any other single instrument you can purchase.

    For more information, please visit:
    https://www.bruker.com/products/surface-and-dimensional-analysis/atomic-force-microscopes/dimension-fastscan/overview.html

  • AFM / LIFE SCIENCE
    JPK NanoWizard® AFM

    Specialized solutions for applications ranging from BioAFM and Polymer Research to Surface Science and NanoOptics

    The NanoWizard® is the most flexible high-end AFM on the market. It sets the benchmark in resolution, speed and stability in particular for fluid applications. All NanoWizard® systems provide true integration of AFM with optical microscopy by means of our patented DirectOverlay™ feature for precise and easy work, and comes with a large variety of options and accessories. In addition, the NanoWizard® family comes with the QI™ Mode, an easy and intuitive imaging mode for quantitative imaging.

    NanoWizard® 4 BioScience AFM
    For applications in Life Science and Soft Matter research on single molecules, living cells and tissues. The system combines highest usability with high-quality measurements. Cutting-edge technology from the pioneers of BioAFM.

    NanoWizard® 4 NanoScience AFM
    For applications in materials and polymer science ranging from nanomechanics and electrochemistry to electrical and magnetic measurements.

    BioMAT™ Workstation
    For opaque samples, combining upright optical microscopy with AFM for surface science and life science.

    NanoWizard® Sense AFM
    The best start in AFM for applications in materials and life science.

    NanoWizard® ULTRA Speed 2 AFM
    High-speed imaging and super-resolution AFM on inverted microscopes, paired with unparalleled flexibility.

    NanoWizard® NanoOptics AFM
    Comprehensive solution for advanced experiments which combine AFM and optical spectroscopy such as TERS, Aperture SNOM and sSNOM, confocal microscopy and nano manipulation in optical fields.

    OT-AFM Combi-System
    NanoTracker™ & NanoWizard® - Powerful combination of Optical Tweezers & AFM in one system for force measurements in 2D and 3D from 500fN to 10nN.

    For more information, please visit:
    https://www.jpk.com/products/atomic-force-microscopy

  • AFM / LIFE SCIENCE / INVERTED MICROSCOPE
    NanoWizard® ULTRA Speed 2 AFM

    A new benchmark: True atomic resolution and high-speed imaging with 10 frames/sec

    The JPK NanoWizard® ULTRA Speed 2 delivers exceptional performance and unmatched user-friendliness. It reaches speed levels previously unattainable with traditional AFMs and combines true atomic resolution and fastest scanning with rates of 10 frames/sec. Real-time, in-situ experiments can be performed in combination with advanced optics. A broad range of modes and accessories makes the system highly flexible and upgradable.

    The NanoWizard ULTRA Speed 2 provides a range of new features:
    • NestedScanner Technology for high-speed imaging of surface structures up to 8µm with outstanding resolution and stability
    • PeakForce Tapping® for easy imaging
    • New tiling functionality for automated mapping of large sample areas
    • V7 Software with revolutionary new workflow-based user interface
    • DirectOverlay™ 2 software for perfect integration and data correlation with advanced fluorescence microscopy platforms
    • Vortis™ 2 controller for high-speed signal processing and lowest noise levels

    High-speed imaging of surface structures up to 8µm with outstanding resolution and stability
    The system comes with the lowest noise and highest stability available on the market to provide true atomic resolution. Direct force control at ultra-low forces prevents damage to your samples and probes. With the state-of-the-art position sensor technology, the system delivers highest accuracy and maximum precision.

    Until now, performing dynamic experiments on living cells, highly corrugated samples or steep surface structures with highest spatial and temporal resolution was challenging. With our new NestedScanner technology, cells, bacteria or structured surfaces with samples heights up to 8µm can now be examined at the highest scan speeds.

    • Observe sample dynamics in real-time with highest resolution
    • Access to corrugated and higher surfaces with the NestedScanner technology
    • Combine AFM and optical fluorescence microscopy for multiparametric in-situ experiments
    • Enhance productivity, probe more sample positions faster

    Key features
    • High-speed imaging with 10 frames/sec with excellent resolution
    • Now with Bruker’s exclusive PeakForce Tapping as standard
    • Revolutionary new workflow-based user interface for ergonomics and ease of operation
    • New tiling functionality for automated mapping of large sample areas together with the HybridStage
    • Unique integration with optical microscopy by tip-scanning design and the newly enhanced DirectOverlay 2 mode for most precise correlative microscopy
    • New Vortis 2 controller with high-speed low-noise DACs and cutting-edge position sensor readout technology
    • Highest flexibility and upgradeability with a broad range of modes and accessories

    For more information, please visit:
    https://www.jpk.com/products/atomic-force-microscopy/nanowizard-ultra-speed-2

  • DESKTOP SEM/ HIGH RESOLUTION/ RE-IMAGINED
    Phenom Pharos Desktop SEM

    "The Thermo ScientificTM Phenom Pharos is a desktop SEM with an FEG source that makes crisp, high-brightness images and the benefits of an FEG source accessible to everyone. It is also easy to operate, from the initial installation to the actual usage, thanks to its intuitive and compact design.

    The advanced hardware design and detectors enable a fast time to image and easy, foolproof handling.

    Phenom Pharos Desktop SEM. Resolution. Re-imagined."

  • Preclinical MRI / in vivo Imaging
    3T MRI

    Translational, Cryogen-free, preclinical MRI – MRS 3000TM Series

    The revolutionary MRS 3000 preclinical MRI systems are leading edge, cost-effective translational preclinical MRI instruments, providing superior soft tissue contrast and molecular imaging capability. The cryogen-free superconducting, dry magnets offer variable field strengths from 0.1T to 3T and have almost no fringe field, allowing safe use in any facility or existing laboratory and by any operator, with low running costs and no special site requirements advancing your small animal research. The MRS MRI systems require NO LIQUID HELIUM, Dry Magnets.

    The MRS 3000 series MRI systems are designed to complement and enable multi-modality imaging. Delivering powerful performance and ease-of-use. The systems are compact with a small footprint design that can be placed in close proximity to other imaging modalities.

    Features & Benefits:

    • Superior soft tissue contrast and molecular imaging capability for great visualization, quantification and translational studies
    • High spatial resolution for great visualization and quantification
    • Superior field homogeneity, minimal noise and no temperature drift
    • Easy translational research with variable field strengths of 0.1T – 3.0T
    • Complete animal handling solution
    • Compact with almost no fringe field
    • Dry magnet, no liquid Helium required
    • Multi-modality imaging; it can be installed in close proximity to other imaging modalities such as SPECT, PET, etc.
    • Available in 17cm or 31cm bore sizes enabling studies with a variety of animal models, e.g. mice, rats, guinea pigs, rabbits, small monkey families and more.

  • Protein Crystallography / Structural Biology / XRD
    XtaLAB Synergy-DW

    One source with two high-flux wavelengths is the foundation of the revolutionary XtaLAB Synergy-DW single crystal X-ray diffractometer. It combines the increased flux of a rotating anode X-ray source with the flexibility of two different wavelengths, making it ideal for laboratories exploring a wide range of research interests.

    Configuration

    The XtaLAB Synergy-DW diffractometer is based on the proven, low-maintenance MicroMax-007 HF microfocus rotating anode. The target is constructed with two different X-ray source materials (Cu and Mo) and is coupled with an auto-switching dual wavelength optic. Copper or molybdenum X-ray radiation is available at the click of a button. The XtaLAB Synergy-DW offers up to 12x higher flux compared to the standard sealed tube X-ray sources and, utilizing only one generator, means overall maintenance is reduced.
    Rounding out the XtaLAB Synergy-DW configuration is the fast and efficient four-circle kappa goniometer which is compatible with a wide range of detectors including the HyPix-6000HE and other Hybrid Photon Counting (HPC) X-ray detectors e.g. PILATUS and EIGER detectors.

    Features:

    • Access to two wavelengths in one compact system
    • 12x higher flux than sealed tube X-ray sources
    • Low maintenance, high performance system
    • Uses CrysAlisPro software with both PX and SMX modes

    Benefits

    • Multi-functional diffractometer to cover you wherever your research takes you
    • High flux performance means you all your crystallography needs can be carried out ‘in-house’
    • Very little downtime and easy maintenance
    • No need to purchase extra software for different applications

  • Protein Crystallography / Structural Biology / XRD
    PX Scanner

    In situ X-ray crystallography system with imager

    The PX Scanner is a fully integrated system for in situ screening and data collection of crystals in SBS crystallization plates and microfluidic chips. This turnkey system combines sample visualization and in situ X-ray screening to deliver a compact tool to evaluate sample quality without the need to remove crystals from their protected growth environment. The system includes a microfocus sealed tube Cu X-ray generator, crystal imaging system, automated tray stage with 6 degrees of tilt, CCD detector and intuitive CrystalEyes software. With the PX Scanner, one can quickly identify whether a crystal contains salt or protein and evaluate diffraction quality for samples without removal from the crystallization plate.

    CrystalEyes software

    The PX Scanner features the CrystalEyes software that allows users to queue screening of multiple crystals from multiple drops for immediate screening. The software includes automatic data reduction tools and an easy to use GUI for reviewing images and X-ray diffraction results.

    Features

    • Microfocus sealed tube Cu source
    • 135 mm CCD detector
    • Touch-screen control for loading and unloading plates
    • Barcode reader for plate identification
    • Compact footprint

  • Protein Crystallography / Structural Biology / XRD
    XtaLAB Synergy-S

    With your success utmost in our minds, we have developed the XtaLAB Synergy-S X-ray diffractometer for single crystal X-ray diffraction. Using a combination of leading edge components and user-inspired software tied together through a highly parallelized architecture, the XtaLAB Synergy-S produces fast, precise data in an intelligent fashion.

    The system is based around the PhotonJet-S series of microfocus X-ray sources that incorporate continuously variable divergence slits. These third generation sources have been designed to maximize X-ray photons at the sample by using a combination of new optics, new, longer life, tubes and an improved alignment system. PhotonJets are available in Cu, Mo or Ag wavelengths in either a single or dual source configuration.

    The XtaLAB Synergy-S single crystal X-ray diffractometer comes with kappa goniometer that incorporates fast motor speeds and a unique telescopic two-theta arm to provide total flexibility for your diffraction experiment. The system is also equipped with your choice of HPC X-ray detector, including the HyPix-6000HE, PILATUS3 R 200K, PILATUS3 R 300K or EIGER 1M.

    Benefits:

    • Extremely high performance due to bright source, noise-free X-ray detector and fast goniometer speeds
    • Continuously variable divergence slit option lets you resolve reflections from long unit cells.
    • Minimal downtime with longer X-ray tube lifetime - supported by online diagnostics and troubleshooting
    • Compact design to fit in your laboratory

    Features:

    • High source flux and increased goniometer speed to allow quicker, more agile experiments
    • Unique telescopic two-theta arm to reach both longer and shorter crystal-to-detector distances
    • Enhanced kappa goniometer design with symmetrical 2θ positioning
    • Improved X-ray optic alignment mechanism for easy maintenance
    • User-inspired cabinet design for improved workflow
    • New electronically controlled brightness of cabinet and crystal lighting

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