High-Resolution FIB-SEM for Life Science Research

Tescan Amber SEM

Product Overview

The AMBER is a state-of-the-art Gallium Focused Ion Beam-Scanning Electron Microscope (Ga FIB-SEM) designed for comprehensive structural analysis of biological samples. It seamlessly integrates high-precision Ga FIB milling with BrightBeam™ Ultra-High-Resolution (UHR) SEM imaging, enabling detailed sub-surface exploration of various biological specimens at both ambient and cryogenic temperatures. This multifunctional workstation is tailored to meet the diverse and challenging requirements of research centers and institutes.

 

Key Features

  • Ambient and Cryogenic Operation: Conduct experiments at room or cryogenic temperatures, accommodating a wide range of biological research needs.
  • Precise Cryo-TEM Lamella Preparation: Utilize the advanced GaFIB Orage™ ion column for artifact-free, on-grid cryo-TEM lamellae preparation.
  • Effortless Cryo Lift-Out: The cryo-nanomanipulator offers smooth, precise movements with intuitive probe tip navigation for easy cryo lift-out procedures.
  • Nanometer-Scale 3D Reconstruction: Achieve high-resolution volume reconstructions using the 3D tomography software package.
  • Integrated Cryo Systems: Enhance cryo-microscopy productivity with fully integrated cryo systems from Leica Microsystems GmbH and Quorum Technologies Ltd, ensuring convenient and safe operation under cryogenic conditions.
  • Safe Navigation with 3D Chamber Model: A unique 3D chamber model provides collision protection, enabling quick and safe navigation to regions of interest.
  • User-Friendly Software Interface: The modular TESCAN Essence™ software offers a variety of pre-designed, guided, and customizable workflow templates, allowing both new and experienced users to operate the microscope efficiently.

 

Specifications

Feature Specification
Ion Source Gallium Focused Ion Beam (Ga FIB)
Electron Source BrightBeam™ Ultra-High-Resolution Scanning Electron Microscope (UHR SEM)
Operational Temperatures Supports both ambient and cryogenic temperatures
Cryo-TEM Lamella Preparation Equipped with GaFIB Orage™ ion column for precise, artifact-free lamellae preparation
Nanomanipulator Cryo-nanomanipulator with smooth, precise movement and intuitive probe tip navigation
3D Reconstruction 3D tomography software package for nanometer-scale resolution volume reconstruction
Cryo System Integration Fully integrated with cryo systems from Leica Microsystems GmbH and Quorum Technologies Ltd for enhanced productivity and safe operation under cryogenic conditions
Navigation and Safety Unique 3D chamber model providing collision protection for quick and safe navigation
Software Interface Modular TESCAN Essence™ software with a variety of pre-designed, guided, and customizable workflow templates
Applications Suitable for nanoscale imaging, routine cross-sectioning, 3D FIB-SEM tomography, and cryo-TEM lamella preparation from cellular plunge-frozen or bulk high-pressure frozen specimens

 

Applications

  • Nanoscale Imaging: From overview to detailed nanoscale imaging, TESCAN AMBER caters to a broad spectrum of imaging requirements.
  • Routine Cross-Sectioning and 3D FIB-SEM Tomography: Expand FIB-SEM capabilities to a wide range of applications, enabling detailed structural analysis.
  • Cryo-TEM Lamella Preparation: Utilize built-in templates for optimized cryo-TEM lamella preparation from cellular plunge-frozen or bulk high-pressure frozen specimens.

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