Accurate Determination of Absolute Molecular Weights
Product Overview
The BI-MwA Molecular Weight Analyzer is a high-precision instrument designed for the accurate determination of absolute molecular weights of proteins, polymers, polysaccharides, and biopolymers. Utilizing multi-angle static light scattering (MALS) technology, the BI-MwA eliminates the need for traditional SEC/GPC column calibration, providing direct measurements without assumptions. Its versatile design allows for operation in both batch and flow modes, making it suitable for a wide range of applications in research and industry.
Key Features
- Multi-Angle Detection: Employs a 7-angle flow cell for precise light scattering measurements.
- Versatile Operation Modes: Supports both batch mode for average molecular weight and flow mode for molecular weight distribution analysis.
- High Sensitivity: Features a temperature-stabilized, precision power-controlled diode laser and a low-noise CCD detector for accurate data collection.
- Comprehensive Analysis: Calculates molecular weight averages (Mn, Mw, Mz), radius of gyration (Rg), and second virial coefficient (A2).
- Compact Design: Small footprint and stackable configuration for efficient laboratory integration.
- Optional Detectors: Can be combined with refractive index (RI) and viscosity detectors for enhanced analysis capabilities.
Specifications
| Specification | Details |
|---|---|
| Laser Source | 30 mW, 660 nm diode laser |
| Detection Angles | 7 fixed angles |
| Detector Type | High-sensitivity, low-noise CCD |
| Flow Cell Volume | Approximately 100 µL |
| Scattering Volume | Approximately 20 nL |
| Operating Modes | Batch and flow modes |
| Measured Parameters | Mn, Mw, Mz, Rg, A2 |
| Software | ParSEC GPC software |
| Optional Accessories | BI-DNDC (RI detector), viscosity detectors |
| Footprint | Compact and stackable design |
| Applications | Proteins, polymers, polysaccharides, biopolymers |
Applications
- Pharmaceuticals: Analyzing protein aggregation, oligomerization, and complex formation.
- Biotechnology: Characterizing biopolymers and polysaccharides for research and development.
- Materials Science: Determining molecular weight distributions of synthetic polymers.
- Chemical Engineering: Studying polymerization kinetics and reaction monitoring.
- Academic Research: Providing accurate molecular weight measurements for various macromolecules.
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